Publications
Rundberg Nilsson, A. What We Thought We Knew About TNF – and What We Must Now Re-learn.
Stem Cell Reports (2026). Accepted.
Antonucci L, Li N, Duran A, Cobo I, Nicoletti C, Watari K, Nandi SP, Zhu F, Zhao Y, Riahi I, Tsuda M, Shah VM, Morgan T, Waugh T, Caputo L, Liu Y, Rundberg Nilsson A, Xian H, Todoric J, Gu L, Sanchez-Lopez E, Eibl G, Vucic EA, Krawczyk M, Xu Q, Lowy AM, Hatzivassiliou G, Roose-Girma M, Skowronska-Krawczyk D, Scott DA, Bar-Sagi D, Tamayo P, Wu Y, Sears RC, Glass CK, Alexandrov LB, Puri PL, Dawson DW, Hu Y, Diaz-Meco MT, Moscat J, Karin M. Self-Amplifying NRF2-EZH2 Epigenetic Loop Converts KRAS Initiated Progenitors to Invasive Pancreatic Cancer.
Nature Cancer (2025). PMID: 40588523. https://doi.org/10.1038/s43018-025-01003-3
Zhang, Q., Rydström, A., Hidalgo, I., Cammenga, J., and Rundberg Nilsson, A. Medium-dose irradiation impairs long-term hematopoietic stem cell functionality and hematopoietic resilience to cytotoxic stress.
International Journal of Biochemistry and Cell Biology (2025). PMID: 40473015. https://doi.org/10.1016/j.biocel.2025.106814
Rundberg Nilsson, A., Xian, H., Shalapour, S., Cammenga, J., Karin, M., IRF1 regulates self-renewal and stress-responsiveness to support hematopoietic stem cell maintenance.
Science Advances (2023). PMID: 37889967. https://doi.org/10.1126/sciadv.adg5391
Rundberg Nilsson, A., Hidalgo, I., Bryder, D., Pronk, CJ. Temporal Dynamics of TNF-Mediated Changes in Hematopoietic Stem Cell Function and Recovery.
iScience (2023). PMID: 36968066. https://doi.org/10.1016/j.isci.2023.106341
Xian, H., Liu, Y., Rundberg Nilsson, A., Crother, T. R., Porrit, R. A., Aleman-Muench, G. R., Lewis, G., Luevanos, M., Trudler, D., Lipton, S. A. Soroosh, P., Arditi, M., Karin, M. and Sanchez-Lopez, E., Metformin inhibition of mitochondrial ATP and DNA synthesis abrogates NLRP3 inflammasome activation and pulmonary inflammation.
Immunity (2021). PMID: 34115964. https://doi.org/10.1016/j.immuni.2021.05.004
Rundberg Nilsson, A., Pronk, CJ. Retinoic Acid Puts Hematopoietic Stem Cells Back To Sleep.
Cell Stem Cell (2017). PMID: 28686871. https://doi.org/10.1016/j.stem.2017.06.002
Tesi B, Davidsson J, Voss M, Rahikkala E, Holmes TD, Chiang SC, Komulainen-Ebrahim J, Gorcenco S, Rundberg Nilsson A, Ripperger T, Kokkonen H, Bryder D, Fioretos T, Henter JI, Möttönen M, Niinimäki R, Nilsson L, Pronk CJ, Puschmann A, Qian H, Uusimaa J, Moilanen J, Tedgård U, Cammenga J, Bryceson YT. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS and neurological symptoms.
Blood (2017). PMID: 28202457. https://doi.org/10.1182/blood-2016-10-743302
Rundberg Nilsson, A., Soneji, S., Adolfsson, S., Bryder D, Pronk CJ. Human Hematopoietic Stem Cell Aging is Associated with Functional Impairments and Intrinsic Megakaryocytic/Erythroid Bias.
PLoS One. 2016. PMID: 27368054. https://doi.org/10.1371/journal.pone.0158369
Galeev R, Baudet A, Kumar P, Rundberg Nilsson A. Nilsson B, Soneji S, Törngren T, Borg Å, Kvist A, Larsson J. Genome Wide RNAi Screen Identified Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs.
Cell Reports (2016). PMID: 26997282. https://doi.org/10.1016/j.celrep.2016.02.082
Rundberg Nilsson, A., Pronk, CJ., Bryder, D. Probing hematopoietic stem cell function using serial transplantation: Seeding characteristics and the impact of stem cell purification.
Experimental Hematology (2015). PMID: 26027791. https://doi.org/10.1016/j.exphem.2015.05.003
Rundberg Nilsson, A., Bryder, D., Pronk, CJ. Frequency determination of rare populations by flow cytometry: a hematopoietic stem cell perspective.
Cytometry Part A (2013). PMID: 23839904. https://doi.org/10.1002/cyto.a.22324